منابع مشابه
Cyclosporin A and Cyclosporin SDZ
Recent studies have shown that cyclosporin A (CsA) may affect ricin A-chain immunotoxin (RTA-IT) therapy. In this study, we evaluated the ability of CsA and its nonirnmunosuppressive analog. SDZ PSC 833, to enhance anti-CD5 T l O l RTA-ITS in vitro. Both 4 pmol/L CsA and 4 pmol/L SDZ PSC 833 significantly and specifically enhanced the cytotoxic activity of T101 RTA-IT on the human lymphoblastic...
متن کاملCyclosporin A and Cyclosporin SDZ
Recent studies have shown that cyclosporin A (CsA) may affect ricin A-chain immunotoxin (RTA-IT) therapy. In this study, we evaluated the ability of CsA and its nonirnmunosuppressive analog. SDZ PSC 833, to enhance anti-CD5 T l O l RTA-ITS in vitro. Both 4 pmol/L CsA and 4 pmol/L SDZ PSC 833 significantly and specifically enhanced the cytotoxic activity of T101 RTA-IT on the human lymphoblastic...
متن کاملOn Yielding and Jointly Yielding Entries of Euclidean Distance Matrices
Abstract An n × n matrix D is a Euclidean distance matrix (EDM) if there exist p, . . . , pn in some Euclidean space such that dij = ||pi − pj ||2 for all i, j = 1, . . . , n. Let D be an EDM and let Eij be the n×n symmetric matrix with 1’s in the ijth and jith entries and 0’s elsewhere. We say that [lij , uij ] is the yielding interval of entry dij if it holds that D+ tE ij is an EDM if and on...
متن کاملA novel form of ubiquitin found in the basidiomycete fungus, Coprinus congregatus.
Ubiquitin is considered one of the most highly conserved eukaryotic proteins. A remarkable 72 out of 76 amino acid residues are invariant in the ubiquitins of fungi, plants and vertebrates. To date, the ubiquitin sequences of only two fungi have been reported, those of Sacchoromyces cerevisiae (1) and Neurospora crassa (2). These fungi are both ascomycetes, and not surprisingly their ubiquitin ...
متن کاملStructures of Meroterpenes Produced by Penicillium sp, an Endophytic Fungus Found Associated with Melia azedarach
O fungo Penicillium sp foi isolado do córtex das raízes de Melia azedarach após a esterilização da superfície de seus tecidos e foi cultivado durante três semanas sobre arroz previamente esterilizado. Um novo meroterpeno, denominado austinoneol, e os meroterpenos já conhecidos 7-β-acetoxi-dehidroaustina, neoaustina e de-hidroaustina foram isolados do extrato metanólico desta cultura. Suas estru...
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ژورنال
عنوان ژورنال: Nature
سال: 1988
ISSN: 0028-0836,1476-4687
DOI: 10.1038/332671c0